molecular formula Ca B1231392 Calcium-41 CAS No. 14092-95-6

Calcium-41

Número de catálogo: B1231392
Número CAS: 14092-95-6
Peso molecular: 40.962278 g/mol
Clave InChI: OYPRJOBELJOOCE-OUBTZVSYSA-N
Atención: Solo para uso de investigación. No para uso humano o veterinario.
  • Haga clic en CONSULTA RÁPIDA para recibir una cotización de nuestro equipo de expertos.
  • Con productos de calidad a un precio COMPETITIVO, puede centrarse más en su investigación.

Descripción

Calcium-41, also known as this compound, is a useful research compound. Its molecular formula is Ca and its molecular weight is 40.962278 g/mol. The purity is usually 95%.
BenchChem offers high-quality this compound suitable for many research applications. Different packaging options are available to accommodate customers' requirements. Please inquire for more information about this compound including the price, delivery time, and more detailed information at [email protected].

Aplicaciones Científicas De Investigación

Radiometric Dating

Geological and Archaeological Applications

One of the primary applications of 41Ca^{41}\text{Ca} is in radiometric dating, especially for geological and archaeological samples that are older than what conventional carbon dating can handle. The isotope is produced through cosmic-ray interactions with calcium in terrestrial materials. Researchers have developed methods to measure 41Ca^{41}\text{Ca} concentrations in samples such as granite, seawater, and bone using advanced techniques like accelerator mass spectrometry (AMS) .

Case Study: Dating Pleistocene Bones

A study focused on the use of 41Ca^{41}\text{Ca} for dating Middle and Late Pleistocene bones demonstrated its effectiveness. The concentrations measured were between 2×10142\times 10^{-14} and 3×10153\times 10^{-15} for contemporary bovine bone samples, indicating the potential for dating remains that are tens of thousands to millions of years old . This capability is particularly useful for dating specimens that have been buried under ice or sediment, where traditional dating methods may fail.

Environmental Monitoring

Assessment of Geological Processes

Another significant application of 41Ca^{41}\text{Ca} is in environmental monitoring, particularly in assessing geological processes. The isotope can be used to study the movement of groundwater and the transport of contaminants through geological formations. By measuring the 41Ca/Ca^{41}\text{Ca}/\text{Ca} ratio in various samples, researchers can gain insights into historical changes in environmental conditions .

Medical Applications

Monitoring Bone Health

In the medical field, 41Ca^{41}\text{Ca} serves as a powerful tracer for monitoring bone metabolism and assessing bone diseases. A pharmacokinetic model has been developed to evaluate its feasibility in clinical settings. This model allows for the monitoring of calcium balance in patients undergoing treatment for conditions like osteoporosis .

Case Study: Clinical Trials for Osteoporosis Treatment

Research conducted at Purdue University utilized 41Ca^{41}\text{Ca} to assess the efficacy of various treatments aimed at preventing bone loss. By measuring the 41Ca/Ca^{41}\text{Ca}/\text{Ca} ratio in urine, researchers could quantify changes in net bone turnover over time. This method offers greater precision than traditional biochemical markers and can track responses to therapy over extended periods .

Summary Table of Applications

Application AreaDescriptionKey Findings/Results
Radiometric Dating Dating geological and archaeological samplesEffective for Pleistocene bones; measures from 2×10142\times 10^{-14} to 3×10153\times 10^{-15}
Environmental Monitoring Assessing groundwater movement and contaminationProvides insights into historical environmental changes
Medical Monitoring Tracking bone metabolism and diseaseHigh precision in assessing treatment efficacy for osteoporosis

Propiedades

Número CAS

14092-95-6

Fórmula molecular

Ca

Peso molecular

40.962278 g/mol

Nombre IUPAC

calcium-41

InChI

InChI=1S/Ca/i1+1

Clave InChI

OYPRJOBELJOOCE-OUBTZVSYSA-N

SMILES

[Ca]

SMILES isomérico

[41Ca]

SMILES canónico

[Ca]

Sinónimos

41Ca radioisotope
Ca-41 radioisotope
Calcium-41

Origen del producto

United States

Synthesis routes and methods I

Procedure details

10 kg batches of sodium perborate were treated in a series of experiments with CaCl2 in a two-stage spray process using in the first stage 1.5 kg of 30% by weight CaCl2 solution and in the second stage 1.5 kg of water, giving a perborate having a calcium content of 1.6% by weight.
Quantity
0 (± 1) mol
Type
reactant
Reaction Step One
Name
Quantity
0 (± 1) mol
Type
reactant
Reaction Step One
Name
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Two
Name
Quantity
1.5 kg
Type
reactant
Reaction Step Three
Name
perborate
Name
calcium

Synthesis routes and methods II

Procedure details

Another aspect of the invention includes an injectible paste having a mixture of a reactive amorphous calcium phosphate powder, the amorphous calcium phosphate having a calcium to phosphorous atomic ratio in the range of about 1.55 to 1.70, and alternatively about 1.55 to 1.65, and alternatively 1.55 to 1.6, and reactive vacant sites, and a second calcium phosphate powder, and an amount of water sufficient to provide the desired consistency. The water is buffered to a physiologically acceptable pH. The paste is hardenable at body temperature.
Name
Quantity
0 (± 1) mol
Type
solvent
Reaction Step One
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Two
Name
calcium
Name
phosphorous
Name
calcium phosphate

Synthesis routes and methods III

Procedure details

The inventors have discovered that simple admixture or combination of L-carnitine, a calcium or magnesium salt, and valproic acid without a suitable solvent is not sufficient to provide an L-carnitine valproate salt of the present invention. After simple admixture or combination without a suitable solvent, L-carnitine retains its objectionable malodor and offensive taste, as well as its hygroscopicity, and valproic acid remains an oil. In contrast, use of the methods of preparing the L-carnitine valproate salt of the present invention as disclosed herein provides a composition of the present invention that is free from objectionable taste and free or nearly free from repugnant odor. Further, an L-carnitine valproate salt of the present invention has different physico-chemical properties from the starting materials. As we discovered and disclose in Example 1, for example, L-carnitine calcium valproate, an embodiment of the present invention, has a melting point of 171.2° C., different from the melting point of L-carnitine (186-190° C.) or valproic acid (an oil at room temperature and above). The 1H-NMR spectrum of L-carnitine calcium valproate (FIG. 2) differs from that of the starting materials (i.e., L-carnitine and valproic acid) and confirms the structure. L-carnitine calcium valproate is soluble in water, and aqueous solutions of this salt provide bioavailable L-carnitine, calcium, and valproate.
Name
L-carnitine calcium valproate
Quantity
0 (± 1) mol
Type
reactant
Reaction Step One
Name
L-carnitine
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Two
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Three
Name
L-carnitine calcium valproate
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Four
Name
Quantity
0 (± 1) mol
Type
solvent
Reaction Step Five
Name
L-carnitine
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Six
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Seven
[Compound]
Name
L-carnitine valproate salt
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Eight
[Compound]
Name
L-carnitine valproate salt
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Nine
Name
L-carnitine calcium valproate
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Ten
Name
L-carnitine
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Eleven
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Eleven
Name
L-carnitine
Name
calcium
Name
valproate

Synthesis routes and methods IV

Procedure details

Eggshell powder is used in the food industry, including animal and human nutritional supplements. Eggshells provide approximately 36-37 percent elemental calcium in addition to traces of phosphorous and other trace elements. Thus, for example, 500 mg of dried powdered eggshell provides approximately 180 mg elemental calcium. This compared vary favorably to other calcium salts. For example, calcium carbonate provides 40 percent elemental calcium, calcium citrate provides 21 percent elemental calcium, calcium lactate provides 13 percent elemental calcium, calcium gluconate provides 9 percent elemental calcium, dicalcium phosphate provides 23 percent elemental calcium (and 19 percent phosphorus), and bone meal provides 20 percent elemental calcium (and 17 percent phosphorus). A single large eggshell has a mass of approximately 6 g and provides approximately 2200 mg of calcium.
Quantity
0 (± 1) mol
Type
reactant
Reaction Step One
Name
calcium
Quantity
180 mg
Type
reactant
Reaction Step Two
[Compound]
Name
calcium salts
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Three
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Four
Name
calcium
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Five
Quantity
0 (± 1) mol
Type
reactant
Reaction Step Six
Name
calcium
Yield
21%
Name
calcium lactate

Descargo de responsabilidad e información sobre productos de investigación in vitro

Tenga en cuenta que todos los artículos e información de productos presentados en BenchChem están destinados únicamente con fines informativos. Los productos disponibles para la compra en BenchChem están diseñados específicamente para estudios in vitro, que se realizan fuera de organismos vivos. Los estudios in vitro, derivados del término latino "in vidrio", involucran experimentos realizados en entornos de laboratorio controlados utilizando células o tejidos. Es importante tener en cuenta que estos productos no se clasifican como medicamentos y no han recibido la aprobación de la FDA para la prevención, tratamiento o cura de ninguna condición médica, dolencia o enfermedad. Debemos enfatizar que cualquier forma de introducción corporal de estos productos en humanos o animales está estrictamente prohibida por ley. Es esencial adherirse a estas pautas para garantizar el cumplimiento de los estándares legales y éticos en la investigación y experimentación.